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Letter of recommendation on behalf of Datre Hiram Wheeler written by a fellow of the Mississippi Medical School."Wheeler is a young man sustaining a good character her started physic with me in 1824 he possesses good talents made good proficiency while with me & I presume will make a useful physician."

Discusses galvanic machine he wishes to construct and requests more information on the particulars of doing so. Asks about completing an order of Eaton's zoological textbook for a class.

Regarding copper ore, believes the specimen sent "a fair average kind." Gives particulars of copper mining in Cornwall, and thinks sending a miner from Cornwall to look at his site would not be wise due to the differing nature of the veins. Advises getting a miner from a limestone district.

Corrections to be made to Phillips’s geological map, "Tabular View." Made additions to "Characteristic Fossils" and cautions on how to use color. Included translations of "Foreign geologic works" for use in The Philosophical Magazine. Requests a copy of Faraday's Chemical Manipulation.

Cover of a letter sent from Malta to Fallsburgh, New York, and held for over a month in its ship quarantined at Boston. Features "SHIP" stamp, a straight-line QUARANTINE stamp, and a Boston stamp. Letter not present.

Recommends Henry Burnham as physician. [Note: Original located in Mason F. Cogswell letters]

Description of the accidental death of their cousin, Samuel Willson, from a gun explosion as he was ramming gun powder in a new piece given to him after the general muster. Notes the physical injuries, the doctors who tended to him, and his death and funeral.

Writing about the importation of a telescope from Paris that has not arrived. Provides instruction about sending it in a case to his wife and suggests he "enter it at the custom as for some Institution if not perhaps you can Invoice it low as they will not know the value of it."

Asking Drury to do something with “the old Doct,” as he has turned verbally and physically violent. Notes family's unsuccessful attempts to intervene with his behavior.

Comments on family illness, seemingly the mumps, which has spread through several members. Describes symptoms of swelling, chills, and poor appetite. Notes death of the wagon-maker's son from dysentery.