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Recipe to cure salt rheum for both topical and ingested medicinal use, signed by Doctor J. Baird of St. Albans, Vermont. Recipe to make lead water. Recipe to cure bone spavin signed by Francis Halcomb and dated March 10, 1861.

Writing in reference to the Royal Medical and Chirurgical Society's discussion of the treatment and recovery of persons suffering from asphyxia due to drowning. Concerned that the Society did not consider the length of the heart's action during cases of asphyxia. Notes his experiments on live animals and believes that contractions of the heart after several minutes of suffocation are not capable of fully circulating the blood. Does not think that once the heart has stopped due to asphyxiation that it can be restarted.

Weather has been poor the past few days, but he gets outside whenever he can. "I think I am on the right Track to get well, I had a good time while I was gone but not so good as I should if I had ben [sic.] well so as to have gone around more." Captain provided him with Dr. Hoofland German bitters. "I have been to see a clairvoyant Dr. and I can put great confidence in her for she has dun [sic.] great cures where other doctors have failed." The clairvoyant diagnosed him with cankers on his lungs and liver, "that has got to come off." Planning on coming down the next month to stay for the Summer if possible. "this doctor says that I would not live but a short time if their [sic.] was not nothing dun [sic.] for the canker, all that has kept me on my feet so long is stimulating drink and that has been Old boborn [sic.] whiskey."

Letter addressed to his cousin describing the alleged success of the medicine prescribed to him by an “Indian Doctor.” Provides updates about the weather and their family. Purchased a house and a boat.

Interested in Treat’s religious opinions because of his expertise in the subject. Refers to recipient no longer publishing in the Investigator, wondering if it is due to censorship of his radical ideas. Wonders if Treat read the previous paper, which featured a discussion of "Materialism etc., vs. Spiritualism etc." Describes A. B. Childs’ spiritual doctrine Whatever Is, Is Right as very shallow and compares it to that of G. W. Lewis, who attempts to "prove his spiritualism by disproving (?) the existence of matter or at least disputing the power in man to recognize the same!!!" Mentions a lecture from Mrs. Bullene, a medium, who claimed to connect with inhabitants of other planets while in the spirit world. "Venus! & were a beautiful feminine intellectual race!!! What do you think of this Friend Treat? There’s hope for old Bachelors yet!" "There are other points I should like to dwell upon, but my wife is urging with all the tenacity of her sex! – Come to bed!" Ends the letter with "United we stand! Divided we fall!"

Contract for shares in the Sugar Creek Eagle Petroleum Company's lands in Plum Township and Troy Township, Pennsylvania.

Writes of Charlotte Cushman's acting as Lady MacBeth and the philosophical questions it raised for him. Night watchmen will ring bells to alert the town of a meteor shower. Provides scientific details on meteors, including their velocity and power, which he compares to contemporary events and practices to provide scale. Describes how meteors gain speed in space, the formation of asteroid belts and new planets, and meteor showers.

Hopes to visit and have a “Hygiene breakfast.” Written on The Herald of Health and Journal of Physical Culture stationery, which includes subscription information and a list of books on health and hygiene by publisher Miller, Wood & Co.

Account of $132 owed to James P. Burke by the estate of J. D. Battle, settled April 25, 1866. Witnessed by G. B. Struther, Justice of the Peace, including two Internal Revenue stamps. Lists charges for medical practices, such as lancing wounds, extracting teeth, delivering children and a placenta, and prescribing medicine from September 1861 – January 1863. Includes charge for tending to an African American child.

Describes how to fit up a room in order to safely house Mary, seemingly a family member experiencing mental illness. "The only way of keeping Mary in A safe place that we can think of is by ceiling up one half of the room with boards and then have 2 inch plank slats spiked to the beam that runs through the middle of the room." Explains that chaining Mary in the center of the room does not provide adequate space for Lydia to "go in and do the needfull for her without Mary's reaching her as Lydia is afraid of her and we are in fear all the time." Hoping for solutions that remove Mary from the home, as "she is perfectly deadfull when she has those ravings spells which is often… living in such fear we cant do it."