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Inquiring whether Augur's machine would be suitable to help him create enlarged copies of dental impressions.

Regarding the sale and acquisition of plants for an exotic florist shop in Syracuse. Mentions rare plants at Mr. Buist’s place.

Letter from Dr. J. H. Hero, a practitioner of the Water-Cure. Suggesting a treatment plan for a woman named Eleanor, who has a cold and pains throughout her body. Includes details about how and when to give Eleanor the treatment baths. Letter is written on a folded sheet of paper with a printed advertisement for the "New Malvern Water-Cure" institution founded by Hero and Dr. Dwight Russell. The advertisement gives a brief explanation of this new institution, scheduled to open April 1, 1854. "We do not rely solely upon the use of water, but bring to our aid mechanical and Electro-Magnetic agencies, and in particular cases, some of the well known milder medicines, believing we can perform more cures in less time, by an Eclectic mode of practices, than by adhering to any exclusive system."

Discussion of local German immigrants and their "marvellous, magnifying & flexible style" in comparison to that of the Anglo Saxons. Receiving the water cure at Kapp’s Hydropathic Clinic and reports an increase in strength and cheerfulness. Kapp referenced what he called a "crisis" point in the condition, which Campbell is approaching. After the crisis occurs, he states that her healing will be "rapid & certain." "I have not the slightest doubt but what a stay of a month or two here would naturally improve you in activity, strength, & cheerfulness." Notes what to pack for a visit and the best route to travel. Discussion of local Native people and "Indian depredations." German population of San Antonio, New Braunfels, and Fredericksburg is split on their views on slavery. Notes German residents forming clubs to learn English, exchange ideas, and scour the nearby region for "Indian signs."

His response was delayed on completing work of his new edition of minerology and its printing. Reflections on the challenges of classifying minerals and the benefit of using them even if imperfect. "It seems to me to be rather the duty of science to have a system in progress, however great its present incapacity - a system to be emended, or pulled to pieces and rebuilt as new developments may require." Comments on his own classifications, providing details on a few minerals.

Writing to her brother and sister in Grandville, Michigan, regarding Daniel’s case of smallpox. Notes members of the family who were vaccinated. Explains that their mother did not believe that Gertrude was sick from the varioloid and took no precautions, resulting in Daniel catching it from her. Describes Daniel praying with family before he “lost his reason” and reports that he went insane three days before he passed away. Neighbors were afraid, and the family was left with no help. Newborn infant was also infected, along with other members of the family, including young Mary who died. Fannie feels this was merciful, as Mary would have been “an idiot and lame” if she had survived. Note from H. D. Scudder states that if he were to move West, mother wouldn’t come as she “thinks the dead are as dear as the living.”

Description of Yeomans’s history with Dr. P. G. Fitch, a patient at the asylum, and requests information on his case. Fitch had fallen ill and during his convalescence showed signs of insanity. Becomes agitated, harried, incoherent, and increasingly violent. Notes the efforts to remedy him, including medicine and blisters, to little effect.

Alarmed that Joseph visited after being exposed to Scarlet Fever, noting its lethality. "If I was thee I would not have him to work for me any more at preasent, for he comes up there twice a day, and brings it with him every time. I would not like to have him come neare the place once a week with it, let alone twice a day. I would rather pay two men to work than one doctor, and if you all get it, thee will have a tremendious doctors bill to pay." Expresses fear of contagion.

Requesting articles from Pierson for the Physio-Medical Recorder, a “radical Reform Medical paper” advocating the rights of women to medical education. Pierson had formerly supplied articles for the Journal of Medical Reform.

Bills due for maintenance of patients from Cumberland County. Lists individuals, items, costs.