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Encloses resolutions adopted by the Board of Trustees of the College of Pharmacy, New York City. Regards standards on imported drugs and the establishment of a national convention of pharmacists.

Writing "to let you kno that I am in the land of the living yet." Mrs. Champin died of smallpox, "she took it in the City." News of acquaintances, the sinking of the Schooner Empire. Advises them to avoid Philadelphia while smallpox "is so bad."

News that Nancy has been ill in the South with the Asiatic Cholera, also called the bloody flux, describing the disease's symptoms, treatment, and spread in the community, including among enslaved people on plantations. "One wealthy planter has a hundred sick servants every one upon the plantation except Arthur Whittle have had the disease…" Anxiety about her health and religious reflections. "Doct Farrar thinks she may be better, and that her throat may not trouble her as much after this; but you know her constitution is already thread bare; and how little confidence I have in what Physicians say."

Copy of a bill for amounts the County of Saratoga owes J[ames] H[enry] Salisbury at the State Laboratory for chemical analysis performed on specimens, per orders of William T. Odell, District Attorney. Describes the processes and analyses performed on samples, noting associated costs.

Responding to news from Bishop Paine of the formation of a committee including the Methodist Reverend Marshall and two other members of the Arkansas Conference to investigate his “pecuniary business." Cottingham purchased the right to sell Newsom’s Tonic Medicine from a man named Rosser, who claimed the medicine was patented. Cottingham sold the rights to several counties before realizing that Rosser had deceived him. Willing to make restitution if the committee feels that is necessary. “I do feel that restitution shall be made to some one, and brethren it is for you to say to whom, and how much.” Hopes the elders will inform Bishop Paine that he is working towards restitution and can take "charge of work in the Texas Conference."

Letter of recommendation for Dr. White of San Francisco who is applying for "resident, or visiting physician of the State Hospital."

Receipt for payment for medical attendance for his child on February 14, 15, 17, and 19, by Dr. Samuel W. Wyman. Receipt for payment for burial of his child on February 22 by David E. Cutter.

2 receipts for items purchased of D. C. Morehead, M.D., "General Agent for Christie's Galvanic and Magnetic Curatives." One is on a partially printed order form, listing out galvanic belts, necklaces and bracelets, magnetic fluid and plasters, as well as almanacs and show cards. With two advertising illustrations showing Zeus seated in a throne holding a staff and lightning bolt. Both bills note a 50% off discount.

Recalls subscribing to the doctor's book Races of Men, which he gave to his son whom the doctor occasionally treated and is now a practicing lawyer in San Francisco. Inquiring about obtaining another "Subscriber's Copy" of the book and to hear more about how the doctor predicted a recent outbreak of yellow fever.

Presenting a copy of the Grammar and Dictionary of the Dakota Language from the Smithsonian, in recognition of the services Mayer has rendered.