Printed circular sent from the Office of the American Home Missionary Society on behalf of the Executive Committee. The Missionary Society's origins and reliance on the public, summarizing the institution's progress. Comments on the number of "Congregations and Missionary districts" aided, increases in church membership, and the importance of preaching. Mentions the Mississippi Valley as a particular example, on account of its rapid population increase and representation in Congress. "The destinies of the Union will be in their hands. If that portion of the country be not brought under the influence of religion now, it cannot, to human view be done at all. Already the infidel is there,--the Socinian, the Universalist, the Roman Catholic is there. Now or never--is the watchword of all the benevolent Societies in reference to that region." Underscores the necessity of Home Missions, the need for more men to help minister, and the role of auxiliary societies. Grateful for the contribution recently sent. Addressed to H. D. Smith, Sec. Aux[iliar]y Dom[estic] Miss[ionar]y Soc[iet]y, Go[u]verneur, St. Laurence Co., N.Y.